Principal Scientist Screening and Assay Technologies

Genmab is focused on the creation and development of innovative and differentiated antibody products, with the aim of improving the lives of cancer patients.

As Principal Scientist of the ‘Screening and Assay Technologies’ team, you will enable researchers across the organization by ensuring access to cutting edge fluorescent imaging and flow cytometry-based technologies. In this brand-new position, you will be a pivotal player in nurturing Genmab’s growth, with a knock your socks off pipeline of new products. If this sounds like you, Genmab might have your desired job as Principal Scientist Screening and Assay Technologies (SAT) in Utrecht

Your role at Genmab

Contributing to all stages of the antibody discovery process. That is what it means to work as Principal Scientist SAT in our newly built laboratories at Genmab

You will manage and expand a rapidly growing imaging facility (6 high content microscopes, including 2 spinning disk confocals), a flow cytometry facility (12 instruments, 2 research associates), and be the technology lead in various outsourced projects and academic collaborations involving 3D image based assays. Furthermore, as an imaging expert you train and advise Genmab scientists in the development of image-based assays. That is where you come in and where you can help us realize our growth ambitions. Responsibilities include but are not limited to:

  • Your up-to-date imaging expertise supports our research aimed at discovery of novel cancer immunotherapies
  • Run an imaging facility, proactively enabling Genmab researchers to leverage light microscopy technologies to answer their scientific questions
  • You are the imaging expert within the organization. As such you support others with the development of image-based assays and image analysis and you educate colleagues in best practices in your field
  • Lead two Research Associates currently operating a flow cytometry facility
  • Contribute to innovative projects within the Lead Discovery & Technology cluster and Participate in other innovation projects within Genmab

In this position, you report to the Director Screening and Assay Technologies

What we ask

A challenging ‘company expert person to go to’ position lies in store for you. That is, of course, if you have the knowledge and experience to fill the role of Principal Scientist SAT. You are someone, who enjoys working in a fast-paced biotechnology environment and to inspire others with your knowledge, enthusiasm and passion for microscopy. Following new technology developments closely, you easily define and deploy a vision in your field of expertise. You are a connector who takes initiative and strives to achieve the goals that are important to Genmab’s therapeutic antibody projects, working closely together in multidisciplinary teams. With an innovative edge, you can think out of the box, ready to try new things.

More specifically, we ask the following of you:

  • PhD in (Cancer) Cell Biology, Immunology or Biotechnology
  • Broad knowledge of and experience in imaging technologies
  • A few years of relevant experience after attaining PhD
  • Previous experience managing a core facility is preferred
  • Extensive experience with multiple fluorescent imaging technologies and applications (e.g., single molecule RNA-FISH, morphology profiling, immune synapse imaging, single cell population analysis, antibody internalization, functional imaging (FRET, FLIM, FRAP, FLIP))
  • Experience with live imaging technologies (for example spinning disk confocal and lattice light sheet)
  • Interest in sample preparation (fixation and clearing protocols) and optimal stain choice for various microscopy techniques
  • Familiarity with protein co-localization measurements using super-resolution setups (eg SIM, PALM, STORM, STED)
  • Broad experience with image data analysis, management and visualization software.
  • Strong affinity with experimental design, data analysis and data flows

Would you like further information before applying? That’s quite understandable. Please send your question(s) to Miranda Barten, miba@genmab.com

Genmab employees work with determination and with respect for each other, consistent with our core values, to achieve our common goals. We give individuals and teams the autonomy to drive development of innovative products and solutions, knowing that integrity is a core value throughout our company. Genmab will offer the successful application a challenging position, where the right candidate will have the opportunity to work with highly specialised people across functions in an informal, multicultural culture, all aiming to make a difference for cancer patients.

Teamwork and respect are central pillars of Genmab’s culture and we therefore ensure an inclusive, open, and supportive professional work environment across our international locations. We believe that fostering workplace diversity across social, educational, cultural, national, age and gender lines is a prerequisite for the continued success of the company. We are committed to diversity at all levels of the company and strive to recruit employees with the right skills and competences, regardless of gender, age, ethnicity, etc.

 

Please note that if you are applying for a position in the Netherlands; Genmab’s policy for all permanently budgeted hires in this location is to offer a temporary agreement for one year, followed by a contract for indefinite time regardless of seniority.

Genmab A/S is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with you application on our website https://www.genmab.com/privacy

ZURICH IMAGE AND DATA ANALYSIS SCHOOL 2019


**ZURICH IMAGE AND DATA ANALYSIS SCHOOL 2019**

Are you a life-scientist needing to quantify microscopy images?
Do you want to learn how to automatically detect objects in images, track spots and cells, build reproducible image processing workflows, deconvolve and enhance microscopy images, and handle massive data? If yes, this school is for you!

What you will learn!
You will learn the fundamentals of image analysis, including basic macro programming in ImageJ/Fiji as well as other software solutions.

In the first part of the week we will also cover the process of image-formation as it pertains to image analysis: Resolution, correct exposure, point-spread functions, detector noise, Shannon’s sampling theorem, and aliasing. All with a clear focus on application in the lab.

In the second half of the week there will be a number of focused topics, building on what was learnt during the first days, including topics such as:

  • Deep Learning for image restoration and segmentation
  • SMLM (Single-Molecule Localisation Microscopy) data analysis
  • Call4Help sessions
  • Hands-on training with image-analysis software solutions such as ilastik and CellProfiler

Time: 18th – 23rd June 2019

Place: ETH, Zurich, Switzerland

Participation fee: 500 CHF (academia) / 1000 CHF (industry)

Deadline: 15th April 2019 (midnight)

For further information please visit this webpage: http://2019.zidas.org/

Szymon Stoma, Beat Schuler & Simon F. Nørrelykke
Image and Data Analysis (IDA) group, Scientific Center for Optical and Electron Microscopy (ScopeM) | EXCITE @ ETH Zurich

Expired: Advanced Microscopist

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Institute of Science and Technology Austria (IST Austria), Austria

The Bio-Imaging Facility of the IST Austria provides state-of the art fluorescence microscopy services, FACS services, as well as custom image analysis and optical development services. We are enlarging our team and are searching for a full time Advanced Microscopist. Are you interested in how your future working place may look like? This video provides a bird’s eye view of IST Austria.

 

Responsibilities

  • Support of basic facility operations: routine care of microscopy equipment, (basic) training of users
  • Support and development of advanced quantitative microscopy-based measurement methods (FLIM, FRAP, FRET, FCS, RICS, TIRF, laser ablation), initiated by research groups
  • Initial projects involve: support in implementation of lattice light sheet microscope, customization of OpenSPIM, optimization of cleared tissue imaging, implementation of adaptive optics
  • Implementation for real-time feedback microscopy and image analysis routines, initiated by research groups
  • Assist in teaching a yearly microscopy course and small workshops

 

Requirements

  • PhD or relevant education involving optical development and/or -engineering
  • Proven experience with building optical setups and the technical aspects of microscopy
  • Familiar with at least some of the following programs / languages: ImageJ/FIJI (advanced), Java, KNIME, LabVIEW, Matlab, Micro-Manager, Python
  • Reliability and ability to work independently and team-oriented
  • Good organizational and project management skills are of great advantage
  • Work experience in an academic environment is advantageous

 

The position will shortly be posted here: (see pdf attached)

https://ist.ac.at/about-ist-austria/open-positions/scientific-services/

 

Additional information:

information about IST Austria: https://ist.ac.at/

Scientific service units @ IST Austria: http://ist.ac.at/ssus

The BioImaging Facility @ IST Austria: http://ist.ac.at/ssus/list-of-facilities/bioimaging-facility/

 

Application:

  • To apply for this position send your application until March 15st, 2019 in one combined pdf (including CV, certificates and references) by e-mail to:  recruiting@ist.ac.at
  • Starting date: July 2019

 

* In case the ink to the video does not work: https://www.youtube.com/watch?v=nVsWLgkx9uE

Post-doc in Biophysics & Image Analysis for ERC funded project

Post-doc in Biophysics & Image Analysis for ERC funded project

What we are looking for
Applications are welcome from early-career scientists with outstanding track records in the fields of image analysis, microbiology, biophysics. Selection of applicants starts immediately.

Job / Project Description
In an ERC funded project, the Kiers group (Evolutionary Biology, VU University) and the Shimizu group (Systems Biophysics, AMOLF) are accepting applications for a post-doc with exceptional skills in image analysis, microscopy, and/or modeling of transport processes in microbes.

Our aim is to track and analyze the dynamics of nutrient transport inside complex fungal networks in symbiosis with host plants. These fungi offer a unique opportunity to study complex flow patterns (bi-directional flow within random-graph networks) in a research context firmly embedded within an important biological question. Specifically, we are interested in the factors organizing fluid flow across fungal filament networks, and how information and resources are shared across these integrated networks.

The successful post-doc will further develop our automated imaging system to measure velocities, flow dynamics, and oscillatory patterns of nutrients within hyphal networks. This will allow us to better understand the evolution of microbial trade strategies.

Cross-discipline collaboration
We offer a unique opportunity for a post-doc to contribute to cutting-edge research into the evolution of symbioses by working at the intersection of Evolutionary Biology and Biophysics. Housed primarily at the AMOLF Systems Biology Lab with Professor Shimizu, the successful candidate will develop a suit of tools to understand what drives oscillatory dynamics across fungal networks. Ultimately, we are interested in understanding whether plant hosts can influence how fungal symbionts distribute and trade their nutrients.

Requirements
• Candidates should hold a Ph.D., with a strong background in image analysis, experimental physics and/or biophysics
• Outstanding publication record
• Excellent ability to communicate in both written and spoken English
• Ability to start within 2 months

Particular preference will be given to candidates with prior experience with image analysis, microbiology and/or modeling fluid dynamics.

Further particulars
VU University Amsterdam is one of the leading institutions for higher education in Europe and aims to be inspiring, innovative, and committed to societal welfare. It comprises twelve faculties and has teaching facilities for 25,000 students.

AMOLF is one of the top research laboratories of the Netherlands Organisation for Scientific Research Institutes (NWO-I), specializing in the physics of complex matter.

The appointment will be for a period of 1.5 years, with potential grant opportunities to follow.

Salary
Payment will be according to the standard regulations, from € 2,427 up to € 3,831 gross per month (salary scale 10) depending on experience and based on a full-time employment.

Application
Applicants are requested to write a letter in which they describe their abilities and motivation, accompanied by a curriculum vitae. Please include the names of two references, including emails, phone numbers and their relationship to you. Please send application in a single pdf-file only.

Applications should be sent to: toby.kiers@vu.nl

Information
For additional information please contact: Prof. Dr. Toby Kiers
phone number +31 (0)20 5987074 e-mail: toby.kiers@.vu.nl
website: www.tobykiers.com

Science Program Manager

Science Program Manager, Imaging

Chan Zuckerberg Initiative, Palo Alto, USA

 

THE ROLE

In this role, you will play a leadership role in supporting the development of new tools and facilitating collaborations in the imaging and microscopy community, especially in the areas of image analysis and visualization for cell biology. Our support of this ecosystem will likely take many forms, including grantmaking to biologists and computational scientists and developing open-source tools among the science community and CZI computational biologists and software engineers.

The ideal candidate will have deep, hands-on expertise in quantitative microscopy, and at least some familiarity with the current open-source imaging software ecosystem (e.g. ImageJ, FIJI. CellProfiler, etc.) and core technologies (Python, TensorFlow, WebGL). Key qualities are (1) an understanding of how biologists want to work with imaging data; (2) a passion for community engagement and open-source development; and (3) strong interpersonal skills and ability to build and work across a diversity of expertise.

### RESPONSIBILITIES
Work closely with Science Program Officers, Computational Biologists, and Technology Staff to help define and lead programs in imaging and microscopy and represent them to the outside community
Collaborate with biologists, imaging scientists, and open-source software developers to help conceive and develop analysis and visualization tools for biological imaging data
Drive internal and external community engagement, including planning and running hackathons and meetings, and engage in outreach to ensure connections to users, standards groups, and existing open-source communities
Support the grantmaking process for current and future programs, including selection, review, process, and relationship management
Identify and engage with existing open-source communities, and help build consensus around standards and methods

### QUALIFICATIONS
PhD degree or equivalent experience in quantitative microscopy or similar field
3+ years of experience analyzing microscopy image data, including the use of common open-source tools (e.g. ImageJ, FIJI, CellProfiler) and at least one modern software analysis or visualization ecosystem (e.g. Python, TensorFlow, WebGL, etc.)
3+ years of experience in physical or virtual community-building activities, including hackathon planning, workshop or conference organization, hosting tutorials, etc.
3+ years working in or helping coordinate open-source software communities

https://boards.greenhouse.io/chanzuckerberginitiative/jobs/1211984?gh_jid=1211984

 

Image Analysis Specialist

Image Analysis Specialist

 

The Novo Nordisk Foundation Centers for Stem Cell Biology (DanStem) and Protein Research (CPR) at the University of Copenhagen are jointly seeking applications for the position of Image Analysis Specialist

The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem) addresses basic research questions in stem cell and developmental biology and has activities focused on the translation of promising basic research results into new strategies and targets for the development of new therapies for cancer and chronic diseases such as diabetes and liver failure. Learn more about DanStem at http://danstem.ku.dk/.

The Novo Nordisk Foundation Center for Protein Research (CPR) promotes basic and applied research on proteins of medical relevance. The research scope spans in silico biology, proteomics, biochemistry and cell biology, and the unifying theme is the identification and functional exploration of proteins and protein pathways involved in disease mechanisms. Learn more about CPR at www.cpr.ku.dk.

Advanced light microscopy is a key technology for a wide variety of research areas at DanStem and CPR. The Centers offer research platforms in imaging and image analysis to support the continually evolving need for microscopy-based applications and to enhance synergy and scientific productivity. We are now seeking a highly motivated and qualified quantitative image analysis specialist to work within the Imaging Research Platform at DanStem and the Protein Imaging Facility within CPR, alongside the light microscopy specialist at both platforms.

For more information on the position and application instructions please see full open position announcement: https://employment.ku.dk/staff/?show=147352

The closing date for applications is July 16, 2018 at 23.59 pm